Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2 (ABCG2) is an ATP-binding cassette (ABC) transporter that has been implicated as a molecular cause of multidrug resistance (MDR) in a variety of cancer cells.It got its name from being cloned from a multidrug-resistant breast cancer cell line, where it was discovered to impart resistance to chemotherapeutic drugs including mitoxantrone and topotecan. As a result, the FDA has designated BCRP as one of the main drug transporters involved in clinically relevant drug disposal.
https://www.pharmafocusasia.com/articles/a-structured-review-on-bcrp-mediated-multidrug-resistance